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Biology — O Level (5090)
O levels/ IGCSE · Cambridge 5090

Biology — O Level (5090)

How your heart pumps 7,000 litres a day, why antibiotics stop working, how one cell becomes a whole person — biology is the science of you and everything alive around you.

Level
O levels/ IGCSE
Syllabus
Cambridge International · 5090
Exam session
June & November
Exam papers
3 papers
Grades
A* to E
Format
Live online classes
$40.00

One-time payment

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About this course

This course prepares students for the Cambridge O Level Biology examination (Syllabus 5090). Students will explore the living world — from the structure of cells to the complexity of ecosystems. Topics include cell biology, nutrition, transport, respiration, excretion, reproduction, genetics, and ecology. The course develops scientific observation, experimental skills, and the ability to apply biological concepts to health, environment, and everyday life. Ideal for students in Grades 9–10 planning to pursue medicine, dentistry, pharmacy, or biological sciences.

What is included

  • Live online classes with your teacher
  • Quizzes and assignments in your student portal
  • Marks and feedback from your teacher
  • Progress your parents can follow
The syllabus

Cambridge O Level Biology (5090)

Checked against the official Cambridge syllabus for exams in 2026, 2027 and 2028

Quick facts

Syllabus code
5090
Cambridge O Level Biology
Exams you sit
3 papers
Paper 1 + Paper 2 + one practical paper (3 or 4)
Total exam time
3 h 45 min – 4 h 15 min
Depends on which practical paper you take
Exam sessions
June & November
Every year
Grades
A* to E
A* is the highest
Teaching time
about 130 hours
Cambridge's guide; usually 2 school years
Calculator
Allowed
In all parts of the exam
Topics
19
From cells to ecosystems

Topic map

1Cells
  • 1.1 Cell structure and function
  • 1.2 Specialised cells, tissues and organs
2Classification
  • 2.1 Concept and use of a classification system
  • 2.2 Features of organisms
3Movement into and out of cells
  • 3.1 Diffusion and osmosis
  • 3.2 Active transport
4Biological molecules
  • 4.1 Biological molecules
5Enzymes
  • 5.1 Enzyme action
  • 5.2 Effects of temperature and pH
6Plant nutrition
  • 6.1 Photosynthesis
  • 6.2 Leaf structure
  • 6.3 Mineral nutrition
7Transport in flowering plants
  • 7.1 Uptake and transport of water and ions
  • 7.2 Transpiration and translocation
8Human nutrition
  • 8.1 Diet
  • 8.2 Human digestive system
  • 8.3 Absorption and assimilation
9Human gas exchange
  • 9.1 Human gas exchange
10Respiration
  • 10.1 Respiration
  • 10.2 Aerobic respiration
  • 10.3 Anaerobic respiration
11Transport in humans
  • 11.1 Circulatory system
  • 11.2 Heart
  • 11.3 Blood vessels
  • 11.4 Blood
12Disease and immunity
  • 12.1 Disease
  • 12.2 Antibiotics
  • 12.3 Immunity
13Excretion
  • 13.1 Excretion
  • 13.2 Urinary system
14Coordination and control
  • 14.1 Mammalian nervous system
  • 14.2 Mammalian sense organs
  • 14.3 Mammalian hormones
  • 14.4 Homeostasis
  • 14.5 Temperature control
  • 14.6 Blood glucose control
15Coordination and response in plants
  • 15.1 Coordination and response in plants
16Development of organisms and continuity of life
  • 16.1 Nuclear division
  • 16.2 Asexual and sexual reproduction
  • 16.3 Sexual reproduction in plants
  • 16.4 Sexual reproduction in humans
17Inheritance
  • 17.1 Variation
  • 17.2 DNA
  • 17.3 Inheritance
  • 17.4 Selection
18Biotechnology and genetic modification
  • 18.1 Biotechnology
  • 18.2 Genetic modification
19Relationships of organisms with one another and with the environment
  • 19.1 Energy flow
  • 19.2 Nutrient cycles
  • 19.3 Ecosystems and biodiversity
  • 19.4 Effects of humans on ecosystems
  • 19.5 Conservation

Exam pattern

Paper 1 — Multiple Choice
40 questions, each with four options. Covers the whole syllabus.
Everyone
30%
1 hour · 40 marks
Paper 2 — Theory
Short-answer and structured questions — diagrams, data, explanations.
Everyone
50%
1 hour 45 minutes · 80 marks
Paper 3 — Practical Test
Real experiments in a lab, based on the experimental skills in the syllabus.
Either Paper 3 or Paper 4
20%
1 hour 30 minutes · 40 marks
Paper 4 — Alternative to Practical
A written paper about experiments: food tests, drawing specimens, planning and evaluating.
Either Paper 3 or Paper 4
20%
1 hour · 40 marks

Every paper is marked by Cambridge. Students who study online usually sit Paper 4, as it needs no lab — your exam centre confirms which practical paper it offers.

Grades

A*, A, B, C, D, E. 'Ungraded' means below E and is not shown on the certificate. Your certificate says GCE O LEVEL.

What it took in June 2026

GradeMarks out of 200Roughly
A*162–168about 81–84%
A135–141about 68–70%
B108–114about 54–57%
C82–88about 41–44%
D70–75about 35–38%
E58–62about 29–31%

Minimum weighted marks out of 200 in June 2026 (the range covers the different paper variants). Boundaries move every series — aim well above them.

Medicine, dentistry and pharmacy routes usually expect an A or A* in Biology and Chemistry.

Full subject guide
Everything about Cambridge O Level Biology (5090)

Why study it, types of questions, command words, what examiners reward, books, common mistakes, a study plan, careers and FAQs.

Read the guide
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